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Great Dane Mixes: 43 Extra-Large Crossbreeds! (With Pictures)

Great Dane mixes and mixed breeds with pictures

Great Danes mixes are known to be gentle giants born from a Great Dane parent and another breed. These mixes are gaining popularity recently and it’s easy to see why. 

If you’re familiar with the size of the Great Dane, you’ll know immediately how hard it is to breed with other dogs. Hence, Great Dane mixes are often products of artificial insemination.

In this guide, you will meet 43 wonderful Great Dane hybrids. We’ll touch on the most popular, the rarest, the cutest, and the most dashing Great Dane mix-breeds. Stick around to learn more!

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43 Great Dane Mixes

When mentioning the Great Danes, the first thing that would come to your mind is their large size. But aside from this, they are an endearing companion with incredible friendliness and calm temperament. 

Being the 16th most popular breed in the United States, they have become a popular choice to mix with other purebreds, hoping to produce the ideal giant breed. 

A cross between these loving dogs is pretty awesome, with a balanced mix between the Great Dane and their other parent. Below, we compiled a list of these amazing Great Dane mixes that you could check out. 

1. Boxane (Boxer & Great Dane Mix) 

Boxane Boxer Great Dane Mix
Image credit: mack.andcheesie / Instagram

The Boxane is a mix between a Boxer and a purebred Great Dane; they are one of the more active Great Dane mixes. They are agile, athletic, and powerful. 

They are highly energetic and very playful. These goofy pooches are also very friendly and are good family dogs. However, they are not suited for families or people who have tiny living spaces. 

The Boxer Great Dane mix is known for being large, muscular, and exuberant. They can weigh from 50 to 190 pounds. They are likely to have short, dense coats with large feet and folded ears. 

This large dog requires plenty of physical activities with extreme play sessions and jogs. It is wise to note that they can get stubborn and sensitive; they need an owner who can manage their strength and size.

2. Great Danesky (Siberian Husky & Great Dane Mix) 

Great Danesky Siberian Husky Great Dane Mix
Image credit: belladanesky / Instagram

This cross between a Siberian Husky and a Great Dane is a regal giant breed. The Great Danesky could weigh up to 190 pounds. This massive dog needs a large amount of space for them to run around.

This Great Dane mixed breed may have the height of a Great Dane and the muscles of a Siberian Husky. Their coat may either be a short coat or a thick double coat.

They may have markings of a Siberian Husky on a Great Dane-looking body. They also shed year-round and more heavily during shedding seasons. 

Both of their parent breeds are protective over and gentle with children, making them suitable for families with kids. However, they may not do well with small animals because they have a high prey drive. 

Great Danes are gentle while Huskies are independent, giving the Great Danesky a well-balanced temperament. They are social, laid-back, and playful at the same time.

3. Corgi Great Dane Mix

Corgi Great Dane Mix
Image credit: mixedbreeddogs / Instagram

Corgi Great Dane mixes are unusual breeds because of their size differences. Their features depend on which gene is more predominant. They could weigh from 22 pounds up to 100 pounds.

Their height usually measures around 12 to 28 inches from the shoulders. They have pointed ears, tapered noses, and short or long coats. They are moderate to light shedders. 

The Corgi Great Dane mix is perfect for first-time dog owners as they are easy-going and good with children. 

They are friendly and active, with a bit of feistiness coming from their Corgi parent, making them wonderful companions. 

Corgi Great Dane mixes are easy to train at home. They love to please their masters and will do anything to receive a reward. Using positive reinforcement methods rather than just giving treats work best for them. 

4. Great Danoodle (Poodle & Great Dane Mix)

Great Danoodle Poodle Great Dane Mix
Image credit: greatdanoodle / Instagram

The Great Danoodle, also known as Great Doodle, is a mix of a Standard Poodle and a Great Dane. 

They are relatively large, weighing around 40 to 190 pounds. They tend to resemble a large Poodle with the head and facial features of a Great Dane. 

They inherited the rectangular head of their Great Dane parent with floppy ears and a Poodle-like muzzle. They also inherited the very minimal shedding of their Poodle parent.

Poodle Great Dane mixes have short or medium coats that are wavy and curly and also come in various colors.

They also inherited the obedience and the eagerness to please from their parent breed, making it easier to train them. They are intelligent and require regular mental stimulation. 

It is necessary to exercise them as they are predisposed to developing bloat. Training, engaging in canine sports, and playing with puzzle toys are recommended for the Great Danoodle.

5. Dane Shepherd (German Shepherd & Great Dane Mix)

Dane Shepherd German Shepherd Great Dane Mix
Image credit: hupaisaakerrassaan / Instagram

The German Shepherd Great Dane mix is also known as Dane Shepherd or Great Shepherd.

This Great Dane mixed breed is energetic with devotion and has the intelligence and working ability of a German shepherd. 

A Great Shepherd is laid-back and patient and will make an excellent guard dog. Socialization is necessary as German Shepherds are known as very suspicious of strangers. 

They are easy to train, but they should start at a very young age. They make wonderful family dogs and are advised not to be left alone for a long time because they are prone to destructive separation anxiety. 

German Shepherd Great Dane mixes weigh around 60 to 190 pounds and measure 28 to 30 inches from the shoulders. 

They have short hair and sometimes can be double-coated with colors ranging from hazel, brown, black, white, sable, or merle.

6. Great Dangle (Beagle & Great Dane Mix)

Great Dangle Beagle Great Dane Mix
Image credit: rhea_ash_evee / Instagram

The cross between a Great Dane and a Beagle is called Great Dangle or BeDane. This unusual mixed dog breed typically comes in large sizes. However, their looks rely heavily on which genes contributed the most. 

Beagle Great Dane mixes usually have short but dense coats that are reasonably easy to groom, and they only shed seasonally. They may have long and floppy ears with a straight tail of a Beagle. 

The Beagle Great Dane mix has high energy levels and will need lots of physical activities. Long walks and hikes are recommended because they are prone to obesity and bloating

Great Dangles are also very friendly and family-oriented dogs. They are affectionate and love spending time with their owner.

They are capable of independence, but it is not advisable to leave them for long periods. 

7. Bull Daniff (Bullmastiff & Great Dane Mix)

Bull Daniff Bullmastiff Great Dane Mix
Image credit: scoobydaniff / Instagram

The Bull Daniff is a mix of a Bullmastiff and a Great Dane. Both parent breeds are massive dogs, making this mix breed a large dog.

They weigh from 105 pounds to 200 pounds and measure 25 to 34 inches from the withers. 

Bullmastiff Great Dane mixes are loyal and loving. They are great companions for children as they love being around kids and are protective over them. They are also playful, intelligent, and easy to train. 

The Bull Daniff is suited for large homes with a yard. They require minimal maintenance like weekly brushing and keeping the spaces between their folds completely dry to prevent infections. 

However, they are not for inexperienced owners because they would need someone who could handle their strength along with their size.

8. Labradane (Labrador & Great Dane Mix)

Labradane Labrador Great Dane Mix

The Labradane is one of the popular Great Dane mixes. A mix between the Labrador Retriever and the Great Dane, this giant hybrid is very affectionate and a family-oriented dog. 

This mixed breed dog is very social, goofy, and loves children, making them a wonderful companion to kids.

However, due to their high prey drive, one should be watchful when having them around small animals. 

These gentle giants could weigh from 80 to 180 pounds and measure 24 to 30 inches from the shoulders, depending on their gender. They have slender but sturdy bodies with short glossy coats

The Labrador Great Dane mix loves being the center of attention and prefers having companions most of the time. They are also extremely active and love outdoor activities. 

Regular walks and lots of playtime are recommended to keep their high energy at bay. 

9. Chi-Dane-Dane (Chihuahua & Great Dane Mix)

Chi Dane Dane Chihuahua Great Dane Mix
Image credit: ilovelucy.doggy / Instagram

The Chihuahua Great Dane mix, also known as the Great Mexican, is one of the rarest Great Dane mixes.

The difference in size is one of the biggest factors behind its rarity. The breeding process is not only risky but also expensive. 

However, if you get a chance to have a Chi-Dane-Dane, you’ll get a great watchdog even when they are just twice the size of a Chihuahua. 

A Chi-Dane-Dane is loyal, friendly, and affectionate; they are gentle and patient enough to be around kids, making a Chi-Dane-Dane a wonderful family pet. They could also fit in families with small living spaces.

Great Danes are easy to train, while Chihuahuas are somewhat hard. The Great Mexican needs positive reinforcement, patience, and consistency during training. Their exercise needs depend on how big or small they come. 

10. Chow Chow Great Dane Mix 

Chow Chow Great Dane Mix

The Chow Chow Great Dane mix is inquisitive and spunky, a trait to watch out for. They are also affectionate and intelligent.

They need long walks and plenty of physical activities to keep them healthy and maintain their energy level. 

They are eager to please and have adorable, expressive faces that would tell how they feel. Like other mixed breed dogs, their traits and features rely on which parent gene is predominant.

However, they are very likely to sport the Chow Chow’s blue tongue and coat colors.

The Chow Chow Great Dane mix is also a rare Great Dane mix. For that reason, information about this mixed breed is scarce. Looking into the parents will help figure out how this breed would be.

11. Border Collie Great Dane Mix

Border Collie Great Dane Mix

A mix between the Border Collie and the Great Dane results in a reliable watchdog that is playful yet loves to cuddle. They are big with lots of excitement inside them. 

Border Collie Great Dane mixes need lots of room to run around and are more suitable in families with older children.

They are not known to be aggressive, but their playfulness and energy may not be advisable for small children. 

They are medium to large dogs that measure 24 to 25 inches from the withers and weigh as little as 70 pounds.

Their coat length varies between long and short and may have different colors, such as their Border Collie parent.

They are also loyal, intelligent, friendly, calm, well-behaved, and easy to train. However, there could be times when they are stubborn and independent, making it difficult to train them.

12. Australian Shepherd Great Dane Mix 

Australian Shepherd Great Dane Mix
Image credit: jackk_attacckk / Instagram

The Australian Shepherd Great Dane mix is energetic, intelligent, and playful. They would do well with children but sometimes would forget they are big dogs and may get overly excited. 

They could weigh from 60 pounds to 120 pounds and measure 20 to 30 inches from the shoulders.

They require plenty of space because of their size and are suited to have experienced owners because of their temperament. 

This mixed breed can be stubborn and independent without proper guidance. Proper socialization and training could make sure they are well-behaved in public settings. 

Aussie Great Dane mixes love hikes and long walks; they need a lot of mental and physical challenges to keep them active. 

They can also be independent. However, when left alone for a long time they can become destructive.

13. Great Dox (Dachshund & Great Dane Mix)

Great Dox Dachshund Great Dane Mix
Image credit: kiraatjeee / Instagram

The Great Dox is also one of the rare Great Dane mixes. Because of their size differences, breeding them is not recommended but is still possible.

Most of their offspring take after the Dachshund size with an elongated body but with large paws from the Great Dane. They have short, sleek hair that’s shiny but could sometimes be coarse. 

They could weigh around 50 pounds, and on average, they are about 16 inches from the shoulders.

Nonetheless, like other mixed-breed dogs, their appearance depends on the genes of the predominant parent.

Dachshund Great Dane mixes are great family dogs and can adapt to small living spaces. 

14. Pug Great Dane Mix

Pug Great Dane Mix
Image credit: patrick_wood_co / Instagram

The Pug Great Dane mix is a rare mixed breed. As a result, there is little information about this Great Dane hybrid.

They could weigh from 28 pounds to 65 pounds and measure from 15 to 25 inches from the withers depending on their size and gender

They have a silky and short coat that can come in black, fawn, brindle, blue, harlequin, or mantle.

This breed is affectionate, energetic, and friendly; they fit in with families that have kids. They love being the center of attention and don’t appreciate being isolated or ignored. 

Pug Great Dane mixes can often appear sluggish and would require regular exercise. Training them could also allow them to behave well in public settings.

15. Great Cocker Spaniel (Cocker Spaniel & Great Dane Mix)

Great Cocker Spaniel Cocker Spaniel Great Dane Mix
Image credit: browniethemanjaboi / Instagram

The Great Cocker Spaniel, also known as the Cocker Dane, is a cross between a Cocker Spaniel and a purebred Great Dane.

They are medium-sized dogs with fur that’s short to medium in length that sheds minimally

Brushing their coats a few times each week is necessary to keep them clean and prevent mats. However, remember not to bathe them frequently as it can dry out their skin. 

They are one of the Great Dane mixes that need lots of attention. They are very lovable and affectionate. They are also very active and need exercise to keep their energy at bay. 

Moreover, Cocker Spaniel Great Dane mixes are capable of independence and would comfortably get along with other dogs. 

16. Saint Dane (Saint Bernard & Great Dane Mix)

Saint Dane Saint Bernard Great Dane Mix
Image credit: emzzor / Instagram

Having two giant breeds as parents, Saint Dane or Great Bernard is a gentle giant that can grow as tall as 32 inches and weigh between 120 and 200 pounds. 

The Saint Bernard Great Dane mix is an intelligent and excellent family dog. They are protective and kid-friendly and get along well with other dogs and pets.

They are suited to live indoors and love being a part of the family. To keep their massive bodies in good shape, they need a lot of exercise and space for plenty of activities. 

However, Saint Danes should not be overworked, as their bodies grow fast and they can easily get injured. 

17. American Bull Dane (American Bulldog & Great Dane Mix)

American Bull Dane American Bulldog Great Dane Mix
Image credit: american.bulldanes / Instagram

The American Bull Dane is one of the popular Great Dane mixed breeds. Their parent breeds are the American Bulldog and Great Dane. They are known as excellent guard dogs because of their attentiveness and bravery.

The American Bull Dane is an agile and powerful Great Dane hybrid. They are large dogs that can range in size between 40 to 200 pounds.

They are known to be adorably relaxed and love cuddling. However, this breed also gets suspicious of strangers as a result of their territorial nature. 

Proper socialization is necessary for the American Bulldog Great Dane mix, and training may be difficult. 

This mixed breed seemingly inherits the Great Dane’s smooth, shiny coat on a muscular body and a long tapered tail. However, they could be flat-faced, which often leads to health problems. 

18. Dane Corso (Cane Corso & Great Dane Mix)

Dane Corso Cane Corso Great Dane Mix
Image credit: athenadanecorso / Instagram

A Dane Corso is half Cane Corso and half Great Dane. They are large, powerful dogs that are laid-back in nature. As a result of complementary temperaments from their parent breeds, they are stable and calm.

A Dane Corso is a great guard dog. However, proper training and socialization are always essential. They are easy to train but need consistency and firmness as they could get stubborn. 

Being easy-going and friendly, a Dane Corso also makes a great family dog. They also seek lots of attention from their owners. 

Unfortunately, they are not suitable for small living spaces due to their massive size. 

The Cane Corso Great Dane mix could weigh over 100 pounds and measure between 27 and 34 inches.

They are taller and skinnier than their Cane Corso parent, with larger, thicker chests and more muscular bodies. 

19. Great Shar-Pei (Shar-Pei & Great Dane Mix)

Great Shar Pei Shar Pei Great Dane Mix
Image credit: evolvedhuman_ra / Instagram

The Great Shar-Pei is a cross between a Shar-Pei and Great Dane. They make excellent guard dogs because of their size alone. Adding to their size, they are naturally protective and territorial. 

This half Great Dane is affectionate and will love spending time with their people.

However, they inherited the aggressiveness of their Shar-Pei parent, and because of that, they may get stubborn when it comes to training.

Their training and socialization should start early on to teach them how to behave well. 

The Shar-Pei Great Dane mix is likely to have short, dense coats and sheds minimally. Grooming them is rather easy as monthly baths and brushing are enough. 

Although, their coat may need conditioning oils to protect it from dryness and excessive odor. 

20. Great Dakita (Akita & Great Dane Mix)

Great Dakita Akita Great Dane Mix
Image credit: withlove_lucky / Instagram

The Great Dakita is a cross between an Akita and a Great Dane. This Great Dane mixed breed is loyal, protective, and courageous. They need a large amount of space to run around and play. 

They are an aggressive breed that reflects their Akita parent’s traits. Training and socialization should start at a young age to mellow the aggressiveness. 

In training them, it is necessary to be consistent and firm. Akitas are known to be quite challenging to train, and Great Dakitas inherited their stubbornness. 

The Akita Great Dane mix could weigh from 110 pounds to 180 pounds and be as tall as 26 to 36 inches. In most cases, they are likely to have a single-layer coat. 

The traits of a Great Dakita depend on which genes of the parent are more dominant. 

21. Blue Heeler Great Dane Mix 

Blue Heeler Great Dane Mix
Image credit: ourdoggozeus / Instagram

The Blue Heeler Great Dane mix is a very good-natured dog. They are extremely intelligent and make great guard dogs. In most cases, they are gentle, loyal, and sweet. 

This dog breed likes staying active and enjoys going for long walks, hikes, and other outdoor exercises. However, they tend to chase small animals when they see one. 

Due to their size and herding instincts, it is best to be cautious when having them around small children. 

Blue Heeler Great Dane mixes are large dogs with short, smooth coats. Their colors usually are solid gray, merle, or blue roan. Their ears can stand upright or hang hound-like against their faces.

22. English Bulldog Great Dane Mix

English Bulldog Great Dane Mix
Image credit: mo.cooper / Instagram

The English Bulldog Great Dane mix resembles an English Bulldog with a slightly longer muzzle. However, they inherited the muscular, athletic build of the Great Dane and also their giant paws. 

English Bulldog Great Dane mixes are gentle, intelligent, and loyal. They are more laid back and prefer lying down or spending time with their owners. 

However, they should do at least a 40-minute exercise to prevent obesity and other health problems that they are predisposed to. A healthy pooch could eat up to three cups of dog food a day. 

They are one of the lesser-known crosses of Great Danes, as a result, there is little and vague information about them.

23. Great Golden Dane (Golden Retriever & Great Dane Mix)

Great Golden Dane Golden Retriever Great Dane Mix
Image credit: oakleythegoldendane / Instagram

The Great Retriever, also known as the Golden Great Retriever, is a cross between a Golden Retriever and a Great Dane. 

These dogs are loving, and with their patient and tolerant nature, they do well in all types of families and are good with children and other animals. 

However, very young children should be watched over when around a Great Retriever as they are enormous and playful. Nonetheless, they are easy to train when started early. 

This mixed breed inherited a Golden Retriever’s high working capability and a Great Dane’s all-around friendliness. 

Golden Retriever Great Dane mixes love being around people, and they do not do well when left alone for long periods and are prone to separation anxiety. 

Their coat varies depending on which parent it will take after. They may have a single-layer coat from the Great Dane or a dense undercoat covered by a weather-resistant medium layer from a Golden Retriever.

24. Great Pyredane (Great Pyrenees & Great Dane Mix)

Great Pyredane Great Pyrenees Great Dane Mix
Image credit: gordy.the.great / Instagram

A mix between the Great Pyrenees and a Great Dane, the Great Pyredane is a giant breed. They are easy-going, calm, and tolerant of kids. 

However, this Great Dane mix inherited the overprotectiveness of its Great Pyrenees parent. 

Early socialization should lessen these territorial tendencies and ensure that they are well-adjusted and well-behaved pups in public settings. 

They are one of the more independent Great Dane mixes, so you won’t have to worry about them developing separation anxiety which their Great Dane parent often suffers. 

The Great Pyredane tends to be vocal and isn’t suited for small living spaces. They could grow over 24 inches and weigh heavier than 100 pounds. 

They may be fluffy or have extremely short hair, but they are most likely to have the tail of a Great Dane. 

25. Bernese Great Dane (Bernese Mountain Dog & Great Dane Mix)

Bernese Great Dane Bernese Mountain Dog Great Dane Mix
Image credit: juneau_the_great_bernese / Instagram

Combining two gigantic breeds, Bernese Mountain Dog and Great Dane, the result is a massive dog called Bernese Great Dane or Berner Dane. This breed is rare, so information about it is scarce. 

Bernese Great Danes are known to be friendly and calm and could get along with everyone and any animal. However, because of their size, socialization and training are recommended. 

Like other mixed breeds, the features of a Bernese Great Dane would depend on which genes are more predominant. Their coat could vary from a longer, thicker coat, a shorter coat, or anywhere in between. 

Looking into both parent breeds would give you an idea of what type of pup you would be getting. 

26. Rhodesian Great Dane (Rhodesian Ridgeback & Great Dane Mix)

Rhodesian Great Dane Rhodesian Ridgeback Great Dane Mix
Image credit: happydogsuna / Instagram

Rhodesian Great Danes are highly energetic large dogs that love the outdoors.

This breed is intelligent and requires plenty of physical and mental activities. With consistent and firm training, they are quick to learn commands. 

They are powerful with an athletic build and could weigh up to 175 pounds.

Their friendliness and patience came from their Great Dane parent and are a perfect complement to the Rhodesian’s even temperament. 

The Rhodesian Great Dane requires lots of attention and may develop negative behaviors when left alone for long periods. Plenty of physical and mental stimuli are recommended to prevent them from getting bored. 

27. Great Danebull (Pitbull & Great Dane Mix)

Great Danebull Pitbull Great Dane Mix

Known as Great Danebull, the Pitbull Great Dane mix resembles a larger Pitbull with a rectangular head of a Great Dane. They are very muscular with a short, dense coat that tends to shed year-round. 

The Great Danebull, despite its intimidating look, is usually quite gentle, which they inherited from their Great Dane parent. They are eager to please, and that makes them very trainable. 

They are also great with kids and love getting attention. However, socialization and training are necessary as they don’t always have good house manners and tend to get overly excited, which may cause harm to young children. 

28. French Bull Dane (French Bulldog & Great Dane Mix)

French Bull Dane French Bulldog Great Dane Mix
Image credit: kite.thefrenchbulldane / Instagram

The French Bulldog Great Dane mix, known as French Bull Dane, resembles both of their parent breeds with a short coat but is on the smaller side due to the inherited size of their French Bulldog parent. 

The French Bull Dane is affectionate, loyal, and playful. This breed loves spending time with people and gets along with other animals. Although they may develop separation anxiety when left alone for long periods. 

They are playful and have moderate energy, and require lots of physical activities to keep their energy levels down. Long walks and lots of play times are recommended. 

29. Great Catahoula (Catahoula Leopard Dog & Great Dane Mix)

Great Catahoula Catahoula Leopard Dog Great Dane Mix
Image credit: ronin_the_catadane_ / Instagram

The Great Catahoula is a mix between a Catahoula Leopard Dog and Great Dane. They inherited the overprotectiveness of their Catahoula parent, making them amazing watchdogs. 

Aside from being great watchdogs, the Catahoula in their blood makes them easier to train as they are known to be working dogs.

Nonetheless, it is better to give them physical activities to lessen their herding and hunting instincts. 

Catahoula Great Dane mixes are fitted with older children as they are very energetic and playful, which may harm younger children, given their size. 

Running and keeping them active may prevent them from getting bored and causing trouble.

30. Doberdane (Doberman & Great Dane Mix) 

Doberdane Doberman Great Dane Mix
Image credit: loki.doberdane / Instagram

The Doberman Great Dane mix, often called Doberdane or Great Doberman, is a giant hybrid dog. 

They can be as tall as 30 inches and weigh from 95 pounds to 190 pounds. They usually have a long, muscular body with a broad chest and floppy ears. 

The Doberdane is characterized by agility, braveness, and overprotectiveness, which they got from their Doberman parent, making them capable watchdogs. 

They are large and highly energetic and tend to play roughly, so leaving them with small children and animals is not advised. For this reason, it is best to have them accordingly socialized early on.

Properly trained and socialized Doberdanes are affectionate, gentle, and very loyal.

31. Great Newfoundland (Newfoundland & Great Dane Mix)

Great Newfoundland Newfoundland Great Dane Mix
Image credit: itsnotjustadogtho / Instagram

The Newfoundland and Great Dane mix is a pretty big and powerful breed. This hybrid, in most cases, weighs around 150 pounds and measures 28 to 32 inches from the shoulders. 

Their coat may vary from short to dense, but usually, they have long-haired coats that need regular brushing and bathing to help manage their shedding. 

They are intelligent but quite stubborn, making training difficult. The Great Newfoundland requires an experienced and firm handler to train them and socially expose them early on.

Even though they look imposing, these large dogs are affectionate and amply friendly.

They love spending time with their family and are prone to separation anxiety when left alone for long periods of time. 

32. Daniff (Mastiff & Great Dane Mix)

Daniff Mastiff Great Dane Mix

A Daniff is a mix between a Mastiff and a Great Dane. This breed is one of the most popular Great Dane mixes.

They are massive, usually falling between 110 and 230 pounds, and can be either laid-back or highly energetic.

These giants are affectionate, gentle, and loyal. They are smart and do well with children. However, they can be stubborn and would require patience and persistence to train.

The Mastiff Great Dane mix will usually resemble a Great Dane, sporting a muscular build, a large head with folds on their faces, which came from their Mastiff parents, and a pair of floppy ears. 

33. Weiler Dane (Rottweiler & Great Dane Mix)

Weiler Dane Rottweiler Great Dane Mix
Image credit: 2blackdanes / Instagram

A Weiler Dane, also known as Daneweiler, is a mix between a Great Dane and a Rottweiler. 

This breed is massive, with its weight ranging from 80 pounds to 190 pounds. They got the Great Dane’s height with the muscular build and broad chest of a Rottweiler

Despite their intimidating looks and size, a Weiler Dane is calm and loves lazing around. They adapt well to small living spaces like apartments as long as they have sufficient amounts of exercise daily.

Rottweiler Great Dane mixes are independent and quite stubborn, which can make training them hard.

They are protective by nature, but when properly socialized, they are amazing with children and have a sweet temperament. 

34. Plush Danois (Anatolian Shepherd & Great Dane Mix)

Plush Danois Anatolian Shepherd Great Dane Mix
Image credit: sirlarsofanatolia / Instagram

Having both parents come from giant breeds, the Plush Danios is a large dog that could weigh around 150 pounds. They can be very territorial and even aggressive if not given appropriate training.

However, because of their vigilant nature, they make excellent guard dogs. Although, they are not recommended for families with small children due to their size and protective nature. 

They can get hostile with strangers. Teaching them what’s right and wrong is necessary. Regular socialization is recommended to prevent them from getting aggressive. 

A Plush Danois usually has a muscular body, a long neck, and a long, curly tail. Their coat is straight, dense, and medium in length. 

35. Bloodhound Great Dane Mix 

Bloodhound Great Dane Mix
Image credit: rufus.doofus / Instagram

The Bloodhound Great Dane mix is a big dog that weighs from 100 pounds to 200 pounds. 

Most of the time, they are extremely laid-back and do not require that much exercise despite their size as long as they have their regular walks every day. 

This mixed breed is people-oriented, great with kids, and loves being around family. They need regular attention and may develop separation anxiety when left alone for long periods. 

They can function independently, and this may cause difficulty in training them. Hounds are not bred to listen to people, and as a result, the Bloodhound Great Dane mix is not that trainable. 

36. Greater Swiss Mountain Dane (Greater Swiss Mountain Dog & Great Dane Mix)

Greater Swiss Mountain Dane Greater Swiss Mountain Dog Great Dane Mix
Image credit: devinbobsein_ / Instagram

The Greater Swiss Mountain Dane is a cross between a Greater Swiss Mountain Dog and a Great Dane. Both are large dogs, making their mix huge too. The Swissdane can weigh from 85 pounds to 190 pounds. 

Their Greater Swiss Mountain Dog parent is known to be tenacious and tireless working dogs, and the Swissdane is expected to be the same. 

Owners should be prepared to provide outlets to prevent destructive behavior from developing. 

Greater Swiss Mountain Danes are more independent and need consistency and firmness in training. When presented with good leadership, they can be easily trainable. 

They are an affectionate, joyful, and gentle breed when properly trained and socialized.

37. Great Weimar (Weimaraner & Great Dane Mix)

Great Weimar Weimaraner Great Dane Mix
Image credit: milo_thegreatweimar / Instagram

The mix between the Weimaraner and the Great Dane is called a Great Weimar or Weimar Dane. 

These dogs are large-sized mutts that could weigh around 55 pounds to 190 pounds. They mostly have a short, smooth coat but could also inherit a long coat. 

This giant pooch has high energy levels and can be vocal, making them not fit for apartments.

They are loving and gentle towards children but may need supervision because they can get overly playful, which may cause harm.

Weimaraner Great Dane mixes also need lots of physical activities and require consistent training. Physical and mental activities are recommended to prevent destructive behavior from developing. 

The Great Weimar is intelligent, making them really trainable. They could quickly learn tricks and follow commands with ease.

However, you might want to take a proactive stance since they are nippy and have a tendency to bark. 

38. American Foxy Dane (American Foxhound & Great Dane Mix)

American Foxy Dane American Foxhound Great Dane Mix
Image credit: bananageorge / Instagram

The American Foxy Dane is a mix between American Foxhound and Great Dane. These dogs are energetic and need lots of playtime. They enjoy long walks and other physical activities. 

American Foxhound Great Dane mixes are in the medium size weighing from 80 pounds to 120 pounds. 

They could look like a perfect mix of both parents, but, like other mixed breeds, their features vary depending on the predominant parent genes.

The American Foxy Dane is intelligent and eager to please, making it easy to train them. They are also very sweet and patient with young children making good additions to families. 

39. Irish Dane (Irish Wolfhound & Great Dane Mix)

Irish Dane Irish Wolfhound Great Dane Mix
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The Irish Dane, also known as the Wolfhound Dane, is a mix between the Irish Wolfhound and the Great Dane.

They are massive with a muscular build and could weigh from 110 pounds to more than 200 pounds. 

While the genes will vary depending on what’s predominant, the Irish Dane will most likely have the head, eyes, and ears of its Great Dane parent. They could have a short to medium, thick coat.

These gentle giants are affectionate and devoted to their families, making them wonderful family pets. They are sweet and enjoy getting along with other pets. They love to cuddle despite their size. 

Training is required for Irish Danes, not because they are aggressive but because of their largeness; they can easily hurt others accidentally. Although they are not as trainable, they are still quick to learn.

40. Neo Daniff (Neapolitan Mastiff & Great Dane Mix)

Neo Daniff Neapolitan Mastiff Great Dane Mix
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Both the Neapolitan Mastiff and Great Dane are giant breeds making this mix a giant as well.

Neo Daniffs can weigh from 150 pounds up to 200 pounds. They have a large square head, floppy ears, and long muscular legs.

This breed is protective of their family but won’t do well as a guard dog because they are friendly and get along with people easily. They love spending time with their people and cuddling up. 

They get along with children making them a perfect family dog, but it is better not to leave them alone with small kids as they are massive and clumsy sometimes. 

They are smart and people-pleasers, so it can be easy to train them. However, they can get stubborn sometimes and put up with some challenges during training.

41. Taylor’s Bulldane (Old Tyme Bulldog & Great Dane Mix)

Taylors Bulldane Old Tyme Bulldog Great Dane Mix
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The Taylor’s Bulldane is a unique breed because of the rarity of the Old Tyme Bulldog. They are large dogs that weigh between 150 and 200 pounds and stand about 25 to 30 inches tall. 

They usually have sturdy and muscular bodies, toned legs, broad chests, small ears, big heads, and lots of extra skin, which they inherited from their Old Tyme Bulldog parent. 

Taylor’s Bulldanes are friendly and get along with older children. However, they are not to be left alone with small kids because of their size. They are also not suited for small living spaces like apartments. 

42. Presa Dane (Presa Canario & Great Dane Mix)

Presa Dane Presa Canario Great Dane Mix
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The Presa Dane is a cross between a Presa Canario and a Great Dane. They are likely to be huge with strong and stocky bodies, broad, muscular chests, wide heads, upright ears, and long straight tails. 

This gentle giant will do well in larger apartments as long as they get enough exercise daily. However, it is better to wait until their bones have fully matured before taking them for a jog. 

Presa Canario Great Dane mixes are great guard dogs despite them not being aggressive. They are loyal and affectionate to their people. Children are often found cuddling and snuggling up to them. 

43. Great Dalmatian (Dalmatian & Great Dane Mix)

Great Dalmatian Dalmatian Great Dane Mix
Image credit: king_the_greatdal / Instagram

The Great Dane Dalmatian mix, sometimes called a Great Dal or Great Dalmatian, is a rare breed. Both parents used to be hunting dogs but recently became more like companion dogs or family dogs.

For that reason, the Great Dalmatian is active, affectionate, and friendly. They can be companion dogs, watchdogs, or work dogs. They are intelligent and enjoy pleasing people, making them easy to train. 

The Great Dalmatian is most likely to inherit the size and coat of its Great Dane parent but will typically have spotted markings resembling its Dalmatian parent.

Even with their large size, they are moderately energetic dogs and would not require excessive exercise.

How Much Does a Great Dane Mix Cost? Puppy Prices & Expenses

Great Dane mix puppy for sale and adoption

Many factors affect the cost of a mixed Great Dane pup, such as the puppy’s bloodline, the breeder’s reputation, and your location. Typically, a puppy costs $600 to $3,000.

Aside from their initial price, their maintenance cost, vaccinations, vitamins, dog food, and toys should be given due consideration as they add up to your financial responsibility.

Below is a list of initial expenses for a Great Dane mix puppy:

Type of ExpenseCost 
Food and Treats$100 – $120
Food and Water Bowls$15 – $35
Bed$50 – $200
Crate$60 – $500
Leashes and Collars$15 – $50
Toys$30 – $50
Grooming Essentials$40 – $180
Deworming, Flea, and Tick Medications$50 – $200
Initial Vet Visits$100 – $300
Initial Vaccine Shots$75 – $200
Neutering or Spaying$50 – $500
Dog License$10 – $20
Microchip$40 – $60
Miscellaneous Supplies$15 – $30
Total Initial Cost$650 – $2,445

It is wise to note that the cost differs from one pup to another. Not all have equal needs, and some usually come with a puppy pack that includes dog food, toys, and collars, depending on the breeders.

Below is a video with additional information about how much a Great Dane costs:

How Much Does A GREAT DANE Cost?

READ NEXT: How Much Does a Great Dane Cost? (2023 Price Guide)

Places to Find Great Dane Mix Puppies for Sale and Adoption

The Great Dane is one unique breed, and their mixed pups are well-loved by lots of dog fanatics. If you’ve decided to get a Great Dane hybrid, it is always good to look into reputable breeders. 

Searching for responsible breeders near you is the best way. Having them around your area would be convenient as they are accessible if something happens to your pup.

However, be cautious when looking for nearby breeders, and stay away from puppy mills and backyard breeders.

If you want to look for Great Dane mix puppies in your area, here are a few sources to try:

  • Greenfield Puppies – Greenfield Puppies ensures that every breeder in their directory complies with all state laws and follows the strict guidelines they provide. They have lots of puppies you can choose from, and they offer Great Dane mix puppies as well. 
  • Lancaster Puppies – Lancaster Puppies is where dog breeders and puppy sellers put up their puppies for sale, including Great Dane mixes. They provide advertisements for them in addition to stud dog services and other puppies for sale-related items.
  • DogsNow – This online marketplace desires to create a comprehensive listing by allowing breeders and puppy sellers to put up listings of mixed breeds such as Great Dane mixes. They also compile listings from various websites to increase the likelihood of finding the perfect puppy for you. 

Aside from the list above, you could also check out our list of Great Dane breeders.

However, one should do diligent while using such resources. Check out our puppy buying guide to learn how to purchase a puppy safely online. 

Aside from buying, adopting from shelters and rescue organizations is another option, and they don’t cost as much.

Listed are some of the rescues and places where you can find a Great Dane mix available for adoption: 

  • Great Dane Friends of Ruff Love – They believe that each dog that they rescue should be handled with top quality even at the expense of time and money. They make sure that before adopting a Great Dane or their mixes, they are properly socialized, have undergone training, and are medically taken care of.
  • Save Rocky the Great Dane Rescue and Rehab – Their goal is to work with animal shelters, humane societies, and other rescue organizations in protecting and looking for the perfect homes for Great Danes and Great Dane hybrids. Not only that, but they also aim to educate people about the need for sterilization of all pets, proper health care, nutritional requirements, and the process of spaying/neutering a pet.
  • Great Dane Rescue Inc. – They are dedicated to finding homes that would care and love for abandoned Great Danes and mixes they rescue. They make sure that their rescues are medically taken care of and have undergone temperament testing and general health evaluation before putting them up for adoption. 

If it is your first time adopting, you should check out our ultimate adoption guide

The guide contains the adoption process, the guidelines, and requirements that are commonly required for adopting, as well as tips you can follow to accomplish your application. 

We also have a list of our best picks of Great Dane rescues that you should check out. 

READ NEXT: 10 Best Great Dane Rescues for Adoption (2023): Our Top 10 Picks!

Final Thoughts 

Great Dane mixes are amazing pets and loving companions. They are affectionate and friendly. There is surely a perfect match for anyone as there are plenty of mixed-breed choices. 

However, it is necessary to have them undergo obedience training and socialization during their early years to make sure you’ll have a well-behaved, well-adjusted, and happy pup. 

Taking care of a Great Dane mix is a big commitment. Most of them are large breeds that need plenty of space and eat lots of dog food. They also seek lots of attention and love from their owners.

Have you found the perfect Great Dane mix for you? If you’ve decided to take care of these affectionate pooches, comment below your experience.